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Trying to Solve the Puzzle that is Neuroma Pain

Posted by Bryan Potok, CPO on

One of the most challenging issues people experience after amputation is pain. And one of the main causes of post-amputation pain which occurs even after the limb has completely healed, are the presence of Neuromas.

Neuroma pain can be very painful along your stump and prosthesis.

What is a Neuroma?

A neuroma is a clump of nerves that form together under the skin of your residual limb after amputation. Neuromas are formed when the nerves attempt to regenerate as part of the healing process, by retracting and forming into a bundle. Along with fibrous repair tissue, they form a tumor, normally non-malignant, which becomes a visible bump under your residual limb’s skin. Since nerves are the parts of our body in charge of transmitting sensations, neuromas can be extremely sensitive to touch, especially when pressed against a foreign object, like your prosthesis.

What are the Symptoms?

A neuroma usually presents as a growth that can be tender to the touch, found under the skin of your residual limb. The pain commonly presents as a shooting sensation whenever the residual limb presses against the prosthesis while walking. Occasionally, neuroma pain occurs even without internal or external stimulation.

Different individuals have varying experiences with neuromas. Some don’t even discover that they have it, as they feel no pain at all. Depending on its size or where the neuroma is located, some are asymptomatic, especially when the severed nerves are located at a point far back under the muscle where it is not subject to a lot of pressure or manipulation. Some experience mild pain. The larger it is and the closer the neuroma is to the areas that often come in contact with external objects (i.e. your residual limb and prosthetic socket), the more severe the pain can be, oftentimes enough to keep a person from wearing his or her prosthesis, or performing even the simplest tasks.

How is it diagnosed?

Problematic neuromas in amputees may sometimes be difficult to detect because pain may be associated with other possible causes, such as infections succeeding amputation, and phantom limb syndrome, among others.

Painful neuromas are diagnosed through a Tinel test. During this test, the doctor taps on the area where he or she suspects the neuroma is located. The presence of a problematic neuroma results in a shooting pain as the area is tapped.


There are various recommended treatment options for neuromas, categorized as Non-medication, Medication or Surgical. If you are suffering from neuroma pain, your medical team may choose one or more of the following approaches:
Ultrasound. This treatment involves the use of heat generated by sound waves, focusing on the affected limb, and is said to decrease inflammation and swelling by increasing blood flow. A study published in the Physiotherapy Journal by F. Uygur showed that ultrasound therapy resulted not only in immediate relief from pain but also in improvements in gait among amputees.

Massage Therapy

Applying various manual techniques on the residual limb is a therapeutic treatment which lessens pain by increasing blood flow, reducing swelling, and alleviating stress and anxiety. It is also said to help your limb develop tolerance to touch and pressure.


This type of therapy is administered regularly, typically through a hand-held machine applied directly on your limb, creating a mild shaking movement that contracts the muscles. The vibration has a numbing effect on the muscles, minimizing pain. In a study conducted by SM Berger, a Consultant Anaesthetist at the North West Regional Pain Relief Center of Hope Hospital, Safford, a big number of amputees who participated found moderate to good degree of pain relief through vibration therapy.

Percussion/Finger Tapping

This approach may seem counterintuitive at the onset, but percussion therapy, when done correctly, is a technique that desensitizes your residual limb, providing immediate, if not long-lasting, relief from neuroma pain. Finger tapping is a common physical therapy technique among amputees with residual limb pain that is easy enough to self-administer.


This involves the insertion of needles in various points of the body, which is said to cause it to release hormones called endorphins. Endorphins have analgesic effects on the body, creating a positive sensation and reducing our perception of pain. A number of studies have found that acupuncture helps relieve chronic pain. It is also said to change how blood pressure and body temperature responds to pain.

Transcutaneous Electrical Nerve Stimulation (TENS)

TENS is one of the most common methods of pain relief that uses electricity. The mild electrical currents produced by electrodes are used to relieve neuroma pain as well as a host of other conditions, such as arthritis, other post-surgical pain, and even incontinence. The electrodes are applied either internally or externally, and, in the case of neuroma, at the exact area where there is a pain.

Modifying the prosthesis socket, in many cases, just adjusting the shape of the prosthesis socket does wonders to alleviate the pain. Adjusting the prosthesis can minimize the neuroma from rubbing against the socket. Having a well-fitting foot can prevent not only neuroma pain but also other limb pain associated with amputation.  


Patients may undergo one or more of the above mentioned non-medication treatments, in tandem with local analgesics and steroids, as non-invasive options to treat neuroma pain. However, if pain persists, doctors may prescribe surgery.

During surgery, the surgeon may cut the nerve far back under the muscle of the affected limb where it will be subject to less physical contact. However, with this technique, there’s a tendency for the neuroma to grow back.

A new, promising approach called Targeted Muscle Reinnervation (TMR) involves applying nerve transfers. It is performed primarily to improve control of an upper limb prosthesis. However, studies showed that TMR may also provide long-lasting relief from neuroma pain. More studies are needed to determine the long-term effectiveness of this approach.

There is no single perfect treatment guaranteed to cure neuroma or the pain associated with it. Until now, medical research is still trying to find more definitive ways to prevent and provide lasting relief from this occurrence.

As with other conditions, it is important to recognize that not every amputee’s journey towards finding the right treatment is the same. Listen to your body, observe, communicate how you feel, and work closely with your medical team to determine what treatment, or combination of treatments, is best for you. With your vigilance, the support of your doctors, prosthetist, and the right treatment, there is hope in finding lasting relief from neuroma pain. 

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  • hi I am new to this I have been a below the knee for 3 years the 29th if this month I have a lot of pain around the bone and the bone sticks up away from the incision I was told that it could be a neuroma with scar tissue wrapped around it need to know how to get rid of the pain

    patricia tirish hoffman on

  • Hi. I have a BK for 72 years and I have dealt with phantom leg pains periodically over that time. I don’t think I have what you call a neuroma. The pains I get are severe and are in the form of shooting pains all the way up through my body. It shakes me. The pains can come in a month, or several months. They seem to be caused by one or several reasons at the same time (a perfect storm). Factors are pressure changes in weather, abuse of the stump and sometimes by depression or emotions.
    My best treatment is 200 to 600 mg of ibuprofen which usually takes the edge off the pain after about an hour or so. Ibuprofen for some reason seems best for nerve pain. Tylenol or even Vicodin had less effects
    On a positive note, the experience of occasional severe pain and its reversal over my life time has given me a unique perspective on dealing with adversity.
    I will be 87 in Sept. and so far I think I am going strong.

    Sylvester Klutchko on

  • I’ve been getting some relief with acupuncture. Actually I’m surprised it’s helping,

    Sharon Vitale on

  • My neuroma was diagnosed with an MRI. I had two cryoablations at U of M that didn’t work. And two nerve blocks that didn’t work. Can’t wear my prosthesis, too much pain. Not sure what I’ll do next.

    Sharon Vitale on

  • I’ve worn a BK limb 58 years seven months. Fit does make a difference but is
    not a guarantee of relief. In Dec. 1960 when accident occurred was given shots\ of
    Morphine. When I went home I had terrible phantom limb pains which after years
    morphed into Neuromas.
    Some doctors claimed since I was given no pain relief for phantom pain…(I would have accidentally killed myself if they had) gates blocking nerves eventually were open for pain directly to my brain. This was opinion of a few pain specialist but they scare me in more ways than one.
    I did hear of a local man that had a nerve block with success. I’ve gone to work so many times in my life with little or no sleep. I now use Vaseline skin lotion on the back of my stump and it is very helpful. I also use
    a rubber Silipos stump sock against my leg and regular stump sock over it.

    Carey on

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